Spotted around the web: Synthetic embryos; Angelman gene therapy

A web-based, patient driven registry for Angelman syndrome: the global Angelman syndrome registry

Angelman syndrome (AS) is a rare neurodevelopmental disorder that is characterised by severe global developmental delays, ataxia, loss of speech, epilepsy, sleep disorders, and a happy disposition. There is currently no cure for AS, though several pharmaceutical companies are anticipating drug trials for new therapies to treat AS. The Foundation for Angelman Therapeutics (FAST) Australia theref...

Myths around Web Services

Comprehensive semantic descriptions of Web services are essential to exploit them in their full potential, that is, discovering them dynamically, and enabling automated service negotiation, composition and monitoring. The semantic mechanisms currently available in service registries which are based on taxonomies fail to provide the means to achieve this. Although the terms “taxonomy” and “ontol...

Ciprofloxacin therapy for Mediterranean spotted fever.

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

ژن درمانی Gene Therapy

Angelman syndrome.

Angelman syndrome is a disorder in humans [2] that causes neurological symptoms such as lack of speech, jerky movements, and insomnia. A human cell has two copies of twenty-three chromosomes for a total of forty-six?one copy from its mother and one from its father. But in the case of Angelman syndrome, the maternal chromosome numbered 15 has a mutation or deletion in its DNA and a gene on the p...